Medical Research



Hirsutism is an abnormal manifestation of androgenic hormones, either due to excessive production (hyperandrogenicity) or abnormal skin sensitivity (so called "idiopathic hirsutism"). There is also pathological hypertrichosis; this is usually genetic, sometimes with a hormonal component, and can occur in both men and women. In women, hirsutism implies the presence of hair on specific areas of the body where it normally only grows on men. These areas include: upper lip, chin, cheeks, chest. Treatments are cosmetic (discolouration of hair and hair removal by various means, including waxing, electric (electrolysis), laser or pulsed light) and sometimes via medication (combined oral anti-androgen therapy).

Hair removal treatment, however, is essential if complete results are to be obtained.

Aim of the study

The aim of the evaluation was to assess the effectiveness and safety of the treatment. To do this, this study based itself on various data: clinical trials, a satisfaction survey, a study report and bibliographic research.

1. Clinical tests

Tests were conducted with E-One on 63 people in Sabouraud Health Centre (Hôpital Saint Louis - Paris) and the Laboratory ATS / Eurofins (Marseille) between 2008 and 2011.

Summary of comments

This 3-year study helps demonstrate the sustainability of long-term treatment with E-One (3 years), as well as its safety.

Efficiency was demonstrated in relation to the conventional reference method: hot wax.

Tolerance was also checked. The appearance of erythema varies little from year to year: 5.2% (1st year), 3.7% (2nd year) and 3.4% last year, and remains weak.

No side effects were reported during the study.

This test has also been the subject of a publication in June 2010, in the Journal of Cosmetic Dermatology, "Randomized study of tolerance and efficacy of a home-use intense pulsed light (IPL) source compared to the hot-wax method ", Hertsel Adhoute, et al. (Periodical WILEY, Inc.), accessible via this link: :

2. Satisfaction survey among patients with hirsutism

Some users chose E-One for the treatment of hirsutism, in combination with or without drug treatment.

Methodology and sequence

Because of the difficulty in obtaining testimonials from users, E-Swin sent an "anonymous satisfaction questionnaire on hirsutism" to all of its customers in 2009, inviting those with hirsutism to respond.

Customers who replied

589 people suffering from hirsutism and using E-One responded to the questionnaire.

Customers under medical treatment

78% suffer from hormonal hirsutism.


  • In terms of performance

    The level of satisfaction ("satisfied" and "very satisfied") reached 66% with E-One, compared to a rate of 44% for those who underwent sessions with a professional. A similar rate of satisfaction (63.3%) ("equally satisfied with E-One" and "more satisfied with E-One") was reached for the 7% of clients receiving treatment, compared to sessions carried out by professionals. No claim of non-performance with E-One was noted.
  • In terms of security

    No problems regarding the safety of the device were noted during the study.

Summary of key findings

  • The number of satisfied female users is significant: 2 out of 3.

  • Almost all of the users who responded said they were suffering from hirsutism, i.e. 589 people. Among the users of E-One, we notice that a significant amount of customers chose the device as a supplementary treatment for their condition.

3. Study report

"A study on the impact of flash exposure by a source of pulsed light (emitted by the device: E-One Clinic from E-Swin) developed for hair removal on tumorigenicity in a melanoma case" covering the period from 23 November 2012 to 7 December 2012, conducted by the CNRS.

Aim of the article

To check the lack of impact of pulsed light emitted by the E-One Clinic device on tumorigenicity in a melanoma case in mice.

The two lots were monitored in order to assess the difference in the development of tumours between those that were flashed and those that were not flashed.


Flashing with E-One on melanoma tumours did not alter the growth of the tumours.

Key results

Tumour growth in the control mice and mice treated with E-One showed no significant difference. When a dose of flash is delivered, the study demonstrates a lack of inhibitory or accelerator effects on tumour proliferation; no evidence of intolerance was observed on healthy peri-tumoral skin exposed to the flash.

General conclusions of the studies


  • In terms of effectiveness, in 100% of cases after 7 sessions (phase I of the study - data 1), E-One was preferred to a conventional hair removal technique.
  • Whether hirsutism is hormonal or idiopathic, pulsed light can achieve a positive result with less abundant hair. Total hair removal is, however, difficult to obtain due to the existence of a specific cause for the hirsutism, unless a possible endocrinal condition is identified and treated, in which case hair stimulation is diminished or even stopped.
  • The satisfaction survey on E-One confirms its efficiency regarding hirsutism, in both of its forms. The 66% satisfaction rate ("very satisfied" and "satisfied") is high, whereas it’s only 44% for those who previously had sessions by a professional. This rate is virtually identical to those customers undergoing treatment (63.63%).

The data collected also shows the psychological consequences of successful treatment by pulsed light on hirsutism (improvement of self-esteem is higher than treatment by electrolysis).


As regards E-One, this was the first time that a device using pulsed light technology has been compared to a popular home hair removal method that’s considered to have a lasting effect: waxing.

Phase I of this study confirms the previous ones conducted in relation to using a device based on IPL. This particular study shows a better tolerance to E-One than to waxing. In all cases, the erythema that appeared remained light; it did not lead to oedema or desquamation. This indication was confirmed during Phase II, in terms of the appearance of erythema or the occurrence of any other side effect.

Thus, the second phase and third phase, during which only the E-One was used, confirms the 2 advantages of the device.

These results confirm the absence of irritating and lasting effects; slight redness lasted for over 24 hours (phase I of the study) in only 3% of cases. No erythema was observed after 24 hours. These effects are also similar to those typically observed in studies on the use of IPL: mild and reversible erythema.

Pulsed light deployed by E-One thus makes for a perfect hair removal tool for the treatment of hirsutism, even more so because prescription medication:

  • is designed to slow down hair growth,
  • hair grows back when medication is stopped.

Hair removal therefore remains a necessity.

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